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Abstract Detail

Symbioses: Plant, Animal, and Microbe Interactions

Anderson, Karaleen [1], Hatch, Mariel [2], Kopp, Olga [2].

Induction of fungal biofilm in species known to cause Mucormycosis and its application to the antifungal activity of Amphotericin B and Thyme oil.

Fungal infections caused by opportunistic pathogens have been growing in clinical importance in the last decade, with a significant increase in infections due to the Zygomycetes, Mucor and Rhizopus and Absidia. These serious and sometimes fatal infections are often associated with biofilm formation. The formation of biofilms is important clinically because biofilms often show an increase in resistance to antifungal agents when compared to free living colonies.
This study aims to investigate both the biofilm formation and the antifungal susceptibility of three species that have been isolated from Mucormycosis infections namely: Rhizopus oryzae, Absidia corymbifera and Rhizomucor Pusillus.
Upon successful biofilm formation, the possible synergistic effects between thyme oil and amphotericin B will be tested. If successful, this combination could allow clinicians to lower the dose of Amphotericin B, thus reducing the side effect while maintaining and utilizing the effective antifungal properties of both the oil and the drug.

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1 - Utah Valley University , Biology , 357 n 800 w, Orem, Utah, 84057, United States
2 - Utah Valley University, 357 n 800 w, Orem, Utah, 84057, United States

Zygomycetes .

Presentation Type: Poster
Session: P, Symbioses: Plant, Animal, and Microbe Interactions
Location: Exhibit Hall/Omni Hotel
Date: Monday, June 26th, 2017
Time: 5:30 PM This poster will be presented at 5:30 pm. The Poster Session runs from 5:30 pm to 7:00 pm. Posters with odd poster numbers are presented at 5:30 pm, and posters with even poster numbers are presented at 6:15 pm.
Number: PSM003
Abstract ID:249
Candidate for Awards:None

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